Food & Feed Additives
L-lysine was first discovered by a scientist known only as Dreschel in 1889, who was able to isolate the amino acid from casein, or milk protein. The exact structure of the molecule was recorded just three years later. Research of L-lysine continued in 1928 when Vickery and Leavenworth prepared it in crystalline form, then completed by Fischer and Weigert when it was completely synthesized.
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L-lysine was first discovered by a scientist known only as Dreschel in 1889, who was able to isolate the amino acid from casein, or milk protein. The exact structure of the molecule was recorded just three years later. Research of L-lysine continued in 1928 when Vickery and Leavenworth prepared it in crystalline form, then completed by Fischer and Weigert when it was completely synthesized.
L-Lysine is one of the eight essential amino acids that cannot be manufactured by the body. Not only is it needed to support proper growth and bone development, but L-Lysine also improves calcium absorption and helps maintain nitrogen balance in the body.
Lysine is an essential amino acid, meaning that it is not able be synthesized in the body. It has the chemical formula HO2CCH(NH2)(CH2)4NH2, and its codons are AAA and AAG. L-lysine is the biologically active form of lysine in animals.
L-lysine is the precursor for many substances that are important in human nutrition. Alpha ketoglutarate is used to convert L-lysine into acetyl-CoA, which plays an essential role in the citric acid cycle. Allysine is also derived from lysine and is used to synthesize collagen and elastin.
L-lysine can be synthesized in the laboratory from dl-α-amino-ε-caprolactam and an enzyme. The commercial production of L-lysine typically relies on fermentation by the bacteria known scientifically as Corynebacterium glutamicum. L-lysine for use in health supplements is typically prepared as L-lysine HCL, which is the hydrochloride salt of L-lysine.
1. Product Name: L-LYSINE MONOHYDROCHLORIDE (USP/FCC) 
2. CAS No.: 657-27-2
3. EINECS No.: 211-519-9
4. HS Code: 29224110
5. Molecule Formula: C6H15ClN2O2
6. Molecule Weight: 182.648 g/mol
7. Assay: 98.5~101.0%
9. Specification: GB 25542-2010 /FCCIV /USP36
10. Packing: 25kg/drum
11.Characteristics: White crystalline powder, Melting point: 263-264 ºC,
alpha: 21 º (c=8, 6N HCl), ter solubility: 65 g/100 mL (20 ºC)
12. Main uses: The most common use of L-lysine HCL in dietary supplementation is to aid with the natural recovery of sores.
13. Storage: Stored in dry and cool place, keep away from stron light, moisture and heat.
14. Available Documentation:
Certificate of analysis
Method of analysis
Material Safety Data Sheet
Non-GMO certificate
Allergery certificate
Viadd Chemical Full Documents
Non- irradiation certificate
Process Flowchart
Certificate of origin
Phytosanitary certificate
Health certificate
15. Shelf Life:Two years under well Storage situation and stored away from direct sun light.
【Specifications】AJI92/USP36
|
Item |
FCCIV |
AJI |
GB |
|
Appearance |
White crystalline powder |
||
|
Assay |
98.5%~101.5% |
98.5%~101.0% |
98.5%~101.5% |
|
Specific Optical Rotation |
+20.3°~+21.5° |
+20.8°~+21.5° |
+20.3°~+21.5° |
|
Chloride |
|
19.12~19.51 |
|
|
Heavy Metals |
≤10mg/kg |
≤0.001% |
|
|
Lead |
|
|
≤5.0mg/kg |
|
Arsenic |
|
≤0.0001% |
≤1.0mg/kg |
|
Iron |
|
≤0.001% |
|
|
Ammonium |
|
≤0.02% |
≤0.02% |
|
Sulfate |
|
≤0.02% |
|
|
Ash |
|
|
≤0.2% |
|
pH |
|
5.0~6.0 |
5.0~6.0 |
|
Loss on drying |
≤1.0% |
≤0.4% |
≤1.0% |
|
Reside on Ignition |
≤0.2% |
≤0.1% |
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【Main Functions】
Increase content of protein;
Improve milk yield of dairy;
Improve dry matter intake;
Improve conversion ratio of feed nitrogen;
Decreased the concentration of urea nitrogen in serum, milk, and urine;
Improve daily gain and carcass quality of beef;
Improve milk quality by increasing protein and fat content;
Increase fertility rate and improve reproductive performance.
1) The L-Lysine could be used as nutrition enhancers to strengthen lysine in foods.
2) It can enhance the hematopoietic function, increase the secretion of gastric juice, improve the utilization rate of protein, increase the resistance to disease, maintain the balance of metabolism, and promote the development of physical and mental development of children.
3) The L-Lysine has the functions of increasing the appetite of livestock and poultry, improving the resistance to diseases, promoting the wound healing and improving the meat quality, and can enhance the secretion of gastric juice, and is the essential substance for synthesizing the brain nerve, the germ cell, the protein and the hemoglobin.
【Applications】
The most common use of L-lysine HCL in dietary supplementation is to aid with the natural recovery of sores.
1. Food grade: nutritional enhancer, used for seasoning in mayonnaise, milk, instant noodles food
2. Medcine grade:preparation for compound amino acid transfusion, improving efficiency of drugs
3. Feed grade: make poultry nutrition balance, improve meat quality and productivity
1.Cholesterol Management. In the liver, l-lysine converts to carnitine which helps your body burn fat. Because of this fat-burning ability, studies have shown that lysine in the diet may result in decreased levels of LDL (or bad) cholesterol.
2.Bone Health. Everyone knows that calcium is critical for strong bones. L-lysine helps the body to absorb the calcium and decreases the excretion of calcium. Some studies also show that l-lysine may increase the activity of bone and collagen building cells. Decreasing the loss of calcium and increasing bone-building activity may slow the bone loss that happens with age.
3.Herpes Prevention. L-lysine may act as an antiviral by blocking the production of the Herpes Simplex Virus. Studies suggest that following a diet rich in lysine (or taking a lysine supplement), while not curing the virus, may prevent outbreaks of genital herpes and cold sores associated with the herpes virus. L-lysine may also help herpes sores heal faster.
4.Proper Body Growth. L-lysine is one of the primary components of proteins. Therefore, it is critical for proper body growth particularly in children. Because it helps your body absorb calcium, l-lysine is also critical for growing bones and other tissues. Low levels of lysine may lead to failure to grow due to a protein deficiency.
5.Anxiety and Stress Reduction. lysine supplements can reduce stress and anxiety in a population that consumed very low levels of l-lysine rich foods.
6.Shingle Relief. Shingles is caused by the same virus that causes chicken pox in children. With shingles, the adult will experience a painful rash usually located on one side of the body along one of the major spinal nerves. While not a cure for shingles, l-lysine may help decrease the duration or intensity of the disease.
7.Pain Relief:Studies are being conducted to determine if l-lysine acts as an anti-inflammatory. If it does, you may be able to get pain relief from an adequate intake of this amino acid.
8.Heart Health. Finally, l-lysine may be effective in decreasing some of the symptoms associated with angina. While the mechanism of action is not known, lysine in conjunction with vitamin C seems to have some effect.
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