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VITAMIN B12 (Cyanocobalamin, Cobalamin)

【Chemical Name】VITAMIN B12 (Cyanocobalamin,Cobalamin)
【CAS No.】68-19-9
【EINECS No.】200-680-0
【Specification】1%,2%,5%(Food Additives), 1%, 0.1%, 5%, 10%(Feed Additives) 1%,5%,10% (Water sobulable feed additives) BP2010, USP32
【Molecular Formula】C63H88CoN14O14P
【Formula Weight】1355.37
【Appearance】Pale red powder,hygroscopic
【Brand】VIADD
【Supplier】Shenyang Viadd Chemical Co.,Ltd.
【Price Email】sales@viaddchem.com

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                                                                                                     ABOUT VITAMIN B12 (Cyanocobalamin, Cobalamin)
VIADD CHEMICAL company is one professional VITAMIN B12 supplier, distibutor and exporter from China, welcome get Vitamin B12 price by email: sales@viaddchem.com

Vitamin B12, which is called VB12 for short, also known as cobalamin, and is one of the B vitamins, is a class of complex organic compounds containing cobalt Corrin class ,and contained trivalent cobalt in similar porphyrin Corrin plane at the center of the ring.It is the largest and most complex vitamin molecule that has been discovered. It is also the only vitamin with metal ion.

The Vitamin B12 crystal is red, it is also called red vitamin.The plant does not contain VB12, and can not produce VB12. The liver is the best source of VB12, then from milk, meat, eggs, fish and so on.VB12 is an essential coenzyme in the synthesis of RNA and DNA. The lack of VB12 in vivo can cause pathological changes in the nervous system such as peripheral nerve and central nervous system.

【Basic Information】

【Chemical Name】VITAMIN B12 (Cyanocobalamin,Cobalamin)

【CAS No.】68-19-9

【EINECS No.】200-680-0

【Specification】1%,2%,5%(Food Additives), 1%, 0.1%, 5%, 10%(Feed Additives) 1%,5%,10% (Water sobulable feed additives) BP2010, USP32

【Molecular Formula】C63H88CoN14O14P

【Formula Weight】1355.37

【Appearance】Pale red powder,hygroscopic

【Synonyms】hemomin;hepacon-b12;hepagon;hepavis;hepcovite;lactobacilluslactisdornerfactor;lldfactor;macrabin

【Chemical Properties】Deep red crystalline or amorphous crystalline powder, odorless and tasteless. Melting point is 210~220 ℃ (carbonized to black). 1g product can be dissolved in 80mL water, soluble in alcohol, insoluble in acetone, ethyl ether or chloroform. Anhydrous is easy to absorb moisture, crystallization of Vitamin B12 in neutral and acidic solution to air and better thermal stability, in alkali, strong acid and reducing agent is not stable, not resistant to light and ultraviolet.

【Characteristics】It is the deep red crystal or crystalline powder, odorless, tasteless, hygroscopic strong. Slightly soluble in water or ethanol, insoluble in chloroform or ether.  Heat-resistant, but in the case of oxidizing or reducing substances (such as vitamin C or hydrogen peroxide, etc.), heavy metal salts and strong acids, alkalis, it can become invalid.

【Commercial Information】

【Delivery】Within 15 days of order date

【Payment】T/T, D/P, L/C

【Origin】China

【Brand】VIADD

【Supplier】Shenyang Viadd Chemical Co.,Ltd.

【Price Email】sales@viaddchem.com

【Certificate】ISO,KOSHER,HALAL,GMP, MSDS, Material Data Sheet, Non GMO,Non Allergen

【Deliver Port】Tianjin/Qingdao

【Documents】Sales Contract, Commercial Invice, Packing List, Weight List, COA, , Cetificate of Origin, Healthey Certificate, FORM A, FORM E, Policy of Indusrance, B/L, Loading container photos, packing photos, shipping advice, etc

【Shelf Life】2 years

【Storage】Kept in dry, cool, and shaded place with original packaging, avoid moisture.
【Packing】

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

【Vitamin B12 Food Additive】

【Vitamin B12 Feed Additive】

【Vitamin B12 Water-Soluble Food Additive】

【Specifications of Vitamin B12】

【Functions of Vitamin B12】
(1) B12 Vitamin Powder can resistance to fatty liver, promote storage of vitamin A in liver

(2) B12 Vitamin Powder can promote cell mature and body metabolism.

(3) B12 Vitamin Powder participates in the manufacturing of bone marrow RBC ,so it can be the treatment of pernicious anemia.

(4) B12 Vitamin Powder ncreases folic acid utilization rate, promote carbohydrate, fat and protein metabolism
 

Detail Functions:
1. To improve the utilization of folic acid, it and folic acid are together with the synthesis of methionine (from high cysteine synthetase) and choline, producing Vitamin B12 application based pioneer substances such as methyl cobalamin and coenzyme B12 in purine and pyrimidine synthesis process, participating in the methylation process in many important compounds. When vitamin B12 deficiency, activities which transferred methyl groups from the methylenetetrahydrofolate reduced to make folic acid into no use of form, leading to folate deficiency.

2.Maintain the metabolism and function of the nerve myelin sheath. Lack of vitamin B12, can cause neurological disorders, degeneration of spinal cord, and can cause severe psychiatric symptoms. Vitamin B12 deficiency can cause peripheral neuritis. Children's lack of vitamin B12 early performance is emotional, dull, slow response, and finally leads to anemia.

3. Promote the development and maturation of red blood cells. The two acyl coenzyme A is converted to succinate coenzyme A, which is involved in the synthesis of three carboxylic acid cycle, in which the synthesis of A is related to the synthesis of heme.

4. Vitamin B12 is also involved in synthesis of deoxy nucleic acid (DNA), metabolism of fat, carbohydrate and protein, increasing the synthesis of nucleic acids and proteins.An overview of vitamin B12, traits, physiological function, application are compiled by  Eastern of Chemicalbook . (2016-12-10)

【Chemical Propeties】

【Main Applications of Vitamin B12】

(1) B12 Vitamin Powder deficiency can lead to anemia and neurological disorders. Can be used in infant food, usage of 10 ~ 30 mu g/kg; In strengthening pinocytosis usage is 2 ~ 6 mu g/kg.

(2) B12 Vitamin Powder is mainly used in the treatment of giant young red blood cell anemia, nutritional deficiencies, uncontrolled hemorrhagic anemia, neuralgia and obstructive diseases.

(3) As feed nutrition fortifier, B12 Vitamin Powder have the function of the anemia, anemia of pernicious anemia, nutritional anemia, parasites are effective dosage of 15 to 30 mg/t.

(4) B12 Vitamin Powder is essential for human body tissue metabolism in the process of vitamins.

Applications in Different Fields:

1. In Medcine Field

1) Vitamin B12 deficiency can lead to anemia and neurological disorders.

Can be used in infant food, usage of 10 ~ 30 mu g/kg;

In strengthening pinocytosis usage is 2 ~ 6 mu g/kg.

2).Vitamin B12 can treat nutritional and pregnancy anemia.

3) Vitamin B12 can treat nerve pain, muscle pain, joint pain.

4)Itamin B12 can treat uncontrolled hemorrhagic anemia, neuralgia and obstructive diseases.

2. In Food Field

Vitamin b17 can be used as food coloring agents in ham, sausage, ice cream, fish sauce and so on.

3. In Feed Field

As feed nutrition fortifier, have the function of the anemia, anemia of pernicious anemia, nutritional anemia, parasites are effective dosage of 15 to 30 mg/t

4. In Cosmetic Field

Vitamin B12 is generally known as hematopoietic vitamin, with excellent effect of skin regeneration, cell regeneration and blood generation it is an important component of the promotion of human metabolism. It can solve some skin problems as follows:

1)Skin tired, dull, dry skin and other issues;

2) Significantly dilute the appearance of fine lines and wrinkles arising due to increasing age;

3)After the repair sun, autumn and winter cold, dry skin caused by swelling, peeling, pain;

4)Pock marks, mosquito bite scars, burns burn scars;

5)After use cosmetic surgery to avoid scarring.

【Vitamin B12 Preparation Products And Raw materials】

【Research History of Vitamin B12】
1. The discovery of vitamin B12, first of all, should be attributed to the research work carried out by the people in the treatment of pernicious anemia named by British physician Addison.The pernicious anemia at that time is a type of cancer that is incurable.

2. In 1926, Minot and Murphy found it can cure the disease by ingestion of large amounts of raw liver , for which they won the 1934 Nobel Prize in physiology and medicine prize. Following the discovery of Minot and Murphy, people successfully cured the disease by liver concentrate.

3. In 1948, the riches, British Smith and Parker et al, respectively from the liver concentrate isolated a red crystal, named for vitamin B12. In the same year, R. west of Columbia University in the United States confirmed by injections of vitamin B12 to effective treatment of pernicious anemia.

4. Then in 1955, D. Hodgkin,et al. using X-ray analysis to determine the crystal structure of vitamin B12. He also won the 1964 Nobel Prize in chemistry in 1972, Woodward successfully completed the total synthesis of vitamin B12.

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