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L-HISTIDINE INTRODUCTION
VIADD CHEMICAL COMPANY IS ONE PROFESSIONAL L-HISTIDINE MANUFACTURER, DISTRIBUTOR AND EXPORTER FROM CHINA, INQUIRY BY EMAIL: SALES@VIADDCHEM.COM
L-Histidine is an essential amino acid for human development which the body cannot produce on its own.
L-Histidine is one of the 22 proteinogenic amino acids. L-Histidine precursor to histamine (H4365 00) and a component of carnosine.
L-Histidine is thought to be a human essential amino acid, mainly children. After years of development, humans begin to synthesize it, and at this time become a non-essential amino acid. L-histidine is a semi-essential amino acid that is particularly important for infants and animals. Can be used as biochemical reagents and pharmaceuticals, but also for the treatment of heart disease, anemia, rheumatoid arthritis and other drugs. Histidine is present in bananas, grapes, meat, poultry, milk and dairy products. In addition, histidine is also present in green vegetables, but less.
【Basic Information】
【Chemical Name】L-HISTIDINE
【CAS No.】71-00-1
【EINECS No.】200-745-3
【HS Code】2933290090
【Specification】Medicine Grade, 99% Min, AJI92, USP31
【Molecular Formula】C6H9N3O2
【Formula Weight】155.15
【Chemical Properties】White crystalline or crystalline powder,odorless,slightly bitter taste. Melting and decomposition at about 277~288 ℃. The imidazole and metal ions are easy to form complex salt. Dissolve in water (4.3g/100ml, 25 ℃), very difficult to dissolve in ethanol, insoluble in ether.
It is commonly used for its hydrochloride, because of minimal solubility and other reasons.
【Synonyms】(s)-1h-imidazole-4-alanin;(s)-1h-imidazole-4-propanoicaci;(s)-4-(2-amino-2-carboxyethyl)imidazole;(s)-alpha-amino-1h-imidazole-4-propanoicacid;1H-Imidazole-4-propanoic acid, alpha-amino-, (S)-;3-(1h-imidazol-4-yl)-l-alanin;4-(2-Amino-2-carboxyethyl)imidazole;alpha-amino-4(or5)-imidazolepropionicacid
【Applications of L-Histidine】
1.L-Histidine used as nutritional supplements
2.L-Histidine is an important component of amino acid transfusion, compound amino acid preparations.
3.L-Histidine Can be used for the treatment of gastric ulcer. Also used for biochemical studies.
4.Nutritional supplement.
5.Used as pharmaceutical raw materials and food additives.
【Commercial Information】
【Packing】inner double layer plastic film, outer fiber can; 25kg/drum
【Shelf Life】2 years
【Delivery】Within 15 days of order date
【Payment】T/T, D/P, L/C
【Origin】China
【Brand】VIADD
【Supplier】Shenyang Viadd Chemical Co.,Ltd.
【Price Email】sales@viaddchem.com
【Certificate】ISO,KOSHER,HALAL,GMP, MSDS, Material Data Sheet, Non GMO,Non Allergen
【Deliver Port】Tianjin/Qingdao
【Documents】Sales Contract, Commercial Invice, Packing List, Weight List, COA, , Cetificate of Origin, Healthey Certificate, FORM A, FORM E, Policy of Indusrance, B/L, Loading container photos, packing photos, shipping advice, etc
【Uses of L-Histidine】
(1) nutritional supplements. It is the very important components of Amino acid infusion and comprehensive amino acid preparations. It can be used in the treatment of gastric ulcer, anemia, allergies and so on.
(2) It is used for biochemical research, medicine for the treatment of gastric ulcer, anemia, allergies and so on.
(3) It is used as amino acid drugs. It is the main components of amino acid infusion and amino acid preparations, for the treatment of gastric ulcer, anemia and angina, aortitis, heart failure and other cardiovascular system disorders.
Adverse reactions and contraindications: low toxicity, adult poisoning>64g/day, such as the injection of hydrochloric acid histidine with headache, flushing and heat.
(4) It is used as a nutrient enhancer, the important component of amino acid infusion and amino acid preparations. It can be used for the treatment of gastric ulcer and biochemical researchment.
(5) It is used for pharmaceutical raw materials and food additives.
【Specifications of L-Histidine】
Item |
AJI92 |
USP31 |
Assay |
99.0~101.0% |
98.5~101.5% |
pH |
7.0~8.5 |
7.0~8.5 |
Specific rotation[a]D020 |
+12.0°~+12.8° |
|
[a]D025 |
|
+12.6°~+14.0°º |
Transmittance(T430) |
clear & colorless |
|
Chloride(Cl) |
≤0.02% |
≤0.05% |
Ammonium(NH4) |
≤0.02% |
|
Sulfate(SO4) |
≤0.02% |
≤0.03% |
Iron(Fe) |
≤10ppm |
≤30ppm |
Heavy metals(Pb) |
≤10ppm |
≤15ppm |
Arsenic |
≤1ppm |
|
Other amino acids |
conforms |
|
Loss on drying |
≤0.20% |
≤0.20% |
Residue on ignition |
≤0.10% |
≤0.40% |
Organic volatile impurities |
|
conforms |
【Functions of L-Histidine】
1. L-Histidine is an extremely important component of amino acid infusion and comprehensive amino acid formulations for the treatment of gastric ulcers, anemia and allergies
2. L-Histidine can be used for prevention and treatment of anemia.
3. L-Histidine can reduce gastric acidity, ease gastrointestinal surgery pain, vomiting and stomach during pregnancy to reduce the burning sensation, inhibition of gastrointestinal ulcers caused by the autonomic nervous. For allergic diseases such as asthma, L-histidine also has effect.
4. L-Histidine can dilate blood vessels, lower blood pressure, angina, heart failure and other diseases for clinical practice.
Histidine is one of the essential raw materials for the synthesis of some pharmaceutical intermediates.
5.L-histidine is a semi-essential amino acid that is particularly important for infants and animals. Can be used as biochemical reagents and pharmaceuticals, but also for the treatment of heart disease, anemia, rheumatoid arthritis and other drugs. Histidine is present in bananas, grapes, meat, poultry, milk and dairy products. In addition, histidine is also present in green vegetables, but less.
【L-Histidine Preparation Products And Raw materials】
Raw materials:D(+)-Glucose-->Α-PROTEIN-->L-Glutamic acid-->AMBERLITE(R) IRC-50-->Soy bean Isoflavone Isoflavone 10-40%-->Histamine
Preparation Products:L-Cystine-->Leuprorelin-->Bilirubin-->ANGIOTENSIN II, HUMAN-->Histamine