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ABOUT VITAMIN H
VIADD CHEMICAL company is one professional VITAMIN H supplier, distibutor and exporter from China, welcome get VITAMIN H price by email: sales@viaddchem.com
D-Biotin, also called Vitamin H, is a colorless, water-soluble member of the group of B-vitamins. Formerly known as vitamin H or coenzyme R. It has many benefits for the hair, skin, and nails.
Vitamin H is composed of a ureido ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.
Subclinical deficiency of Biotin can cause mild symptoms, such as hair thinning or skin rash typically on the face. Thus, This product is recommended for general food fortification and dietary supplement applications.
D-Biotin can be used for baby food and dietetics, for solid and liquid pharmaceutical preparations, for cosmetic preparations, and for use in the fermentation industry.
【Basic Information】
【Chemical Name】VITAMIN H (BIOTIN)
【CAS No.】58-85-5
【EINECS No.】200-399-3
【Other Names】D-Biotin;Biotin; Vitamin B7;Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid;Vitamin H (D-Biotin); D-Biotin pure;VH;
【Specification】USP35,EP7
【Molecular Formula】C10H16N2O3S
【Formula Weight】244.3032
【Synonyms】RONACARE(TM) BIOTIN PLUS;PHOTOPROBE(R) BIOTIN;VITAMIN B7;VITAMIN H;BIOTIN(V-H);BIOTINUM;BIOTIN, IMMOBILIZED ON DEXTRAN-LYSINE;BIOTIN, IMMOBILIZED ON DEXTRAN
【Functions】
1)Biotin(Vitamin H ) is the essential Nutrients of the retina,the Biotin deficiency could cause the Dry eyes, keratization, inflammation, even blindness.
2)Biotin(Vitamin H) can improve the body's immune response and resistance.
3)Biotin(Vitamin H) can maintain normal growth and development.
4)Biotin(Vitamin H) deficiency will cause reproductive functions recession, bad bone growth and the obstruction of embryo and early childhood growth.
6) To help fat, glycogen and the synthesis and metabolism of amino acids in the human body is normal;
7) To promote sweat glands, nerve tissue, bone marrow, the male gonads, the skin and hair of normal operation and the growth, relieve eczema, dermatitis symptoms;
8) To prevent white hair and hair loss, help to cure baldness;
9) To ease muscle pain;
10) Promote the synthesis of urea and excretion, purine synthesis and biosynthesis of oleic acid.
11) For the treatment of atherosclerosis, stroke, lipid metabolism disorders, high blood pressure, coronary heart disease and blood circulation disorder diseases.
【Commercial Information】
【Delivery】Within 15 days of order date
【Payment】T/T, D/P, L/C
【Origin】China
【Brand】VIADD
【Supplier】Shenyang Viadd Chemical Co.,Ltd.
【Price Email】sales@viaddchem.com
【Certificate】ISO,KOSHER,HALAL,GMP, MSDS, Material Data Sheet, Non GMO,Non Allergen
【Deliver Port】Tianjin/Qingdao
【Documents】Sales Contract, Commercial Invice, Packing List, Weight List, COA, , Cetificate of Origin, Healthey Certificate, FORM A, FORM E, Policy of Indusrance, B/L, Loading container photos, packing photos, shipping advice, etc
【Packing】20kg or 25kg/bag/drum/carton box/requested
【Shelf Life】2 years
【Specification of VITAMINE H】USP35
Items |
Specifications |
1. Description |
White or almost white crystalline powder |
2. Identification 2.1. Identification(IR) <197K> 2.2. Specification Rotation[α]25D 2.3. Retention Time |
Match with the Reference IR Spectrum +89° – +93° Should be similar to that of the reference solution |
3. Loss on drying |
≤ 0.4%, in-house |
4. Residual Solvents<467> 4.1 Benzene 4.2 Toluene 4.3 DMSO |
≤ 2ppm,in-house ≤ 100ppm,in-house ≤ 5000ppm,in-house |
5. Assay |
97.5-100.5% |
6. Related Substance Any impurity Total impurities |
≤ 1.0% ≤ 2.0% |
7. Microbiological tests |
|
Total viable aerobic count |
≤ 1000cfu/g, ,in-house |
Total yeasts and moulds count |
≤ 100cfu/g,in-house |
Escherichia coli |
n.d./lg, in-house |
Pseudomonas aeruginosa |
n.d./lg, in-house |
Enterobaceria |
n.d./lg, in-house |
Staphylococcus aureus |
n.d./lg, in-house |
Salmonella |
n.d./10g, in-house |
【Applictions of Vitamin H】
1.Hair problems:
Biotin supplements are often recommended as a natural product to counteract the problem of hair loss in both children and adults. The signs and symptoms of biotin deficiency include hair loss which progresses in severity to include loss of eye lashes and eye brows in severely deficient subjects. Some shampoos are available that contain biotin, but it is doubtful whether they would have any useful effect, as biotin is not absorbed well through the skin.
2.Cradle Cap (Seborrheic Dermatitis):
Children with a rare inherited metabolic disorder called phenylketonuria (PKU; in which one is unable to break down the amino acid phenylalanine) often develop skin conditions such as eczema and seborrheic dermatitis in areas of the body other than the scalp. The scaly skin changes that occur in people with PKU may be related to poor ability to use biotin. Increasing dietary biotin has been known to improve seborrheic dermatitis in these cases.
3.Diabetes:
Diabetics may also benefit from biotin supplementation. In both insulin-dependent and non-insulin-dependent diabetes, supplementation with biotin can improve blood sugar control.
【Chemical Properties】
Melting point: 231-233 °C(lit.)
Alpha: 89 º (c=1, 0.1N NaOH)
Refractive index: 90.5 ° (C=2, 0.1mol/L NaOH)
Storage temp.: 2-8°C
Solubility: H2O: 0.2 mg/mL Solubility increases with addition of 1 N NaOH.
Form: powder
PH:4.5 (0.1g/l, H2O)
Water Solubility:Soluble in hot water, dimethyl sulfoxide, alcohol and benzene.
Sensitive : Light Sensitive
Merck: 14,1231
BRN: 86838
Stability: Stable, but light sensitive. Incompatible with strong oxidizing agents, strong bases, strong acids, formaldehyde, chloramine-T, nitrous acid.
CAS DataBase Reference: 58-85-5(CAS DataBase Reference)
NIST Chemistry Reference: Biotin(58-85-5)
【D-Biotin Preparation Products And Raw materials】
Preparation Products: L-Glutamic acid-->L-Lysine hydrochloride-->Monosodium glutamate-->L-(+)Sodium glutamate
Raw materials: L-Cysteine
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