VITAMIN B3 (Niacin)
【Chemical Name】VITAMIN B3 (Niacin, Niacinamide, Nicotinic Acid)
【CAS No.】59-67-6
【EINECS No.】200-441-0
【Other Names】Nicotinic acid, Niacin; Vitamin PP; 3-Pyridinecarboxylic acid; 3-Carboxypyridine
【Specification】Food grade, Feed grade, Pharma Grade
【Molecular Formula】C6H5NO2
【Formula Weight】123.11
【Appearance】white crystals or crystalline powder
【Supplier】Shenyang Viadd Chemical Co.,Ltd.
【Price Email】sales@viaddchem.com

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Description

                                                                                                     ABOUT VITAMIN B3 (NIACIN, NIACINAMIDE, NICOTINIC ACID)
VIADD CHEMICAL company is one professional VITAMIN B3 (NIACIN) supplier, distibutor and exporter from China, welcome get price by email: sales@viaddchem.com

Vitamin B3 is a water-soluble vitamin, the product is white powder, odorless or nearly odorless, bitter in taste,freely soluble in water or ethanol, dissolvable in glycerin.

Vitamin B3 is easy to absorb oral, and can be widely distributed in the body, the excess metabolites or prototype quickly expel from urine. Nicotinamide is part of coenzyme I and coenzyme II, plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism, maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role.In addition, Vitamin B3 has prevention and treatment of heart block, sinus node function and anti-fast experimental arrhythmias, niacinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.

 

Basic Information

Chemical NameVITAMIN B3 (Niacin, Niacinamide, Nicotinic Acid)

CAS No.59-67-6

EINECS No.200-441-0

Other NamesNicotinic acid, Niacin; Vitamin PP; 3-Pyridinecarboxylic acid; 3-Carboxypyridine

SpecificationFood grade, Feed grade, Pharma Grade

Molecular FormulaC6H5NO2

Formula Weight123.11

Appearancewhite crystals or crystalline powder

Chemical PropertiesWhite crystal or crystalline powder, odorless or has a slight odor, slight sour taste. Melting point is 234-237. Easily soluble in hot water, hot ethanol, alkaline water, propylene glycol, and chloroform. Slightly soluble in water and ethanol; 100ml room temperature water can dissolve 1.6g. Insoluble in ether and ester solutions. The PH of 1% aqueous solution is 3.0-4.0. Stable in heat, acidity and alkalinity.

 

Uses

1. This product is a type of vitamin supplement, and it is called vitamin PP along with nicotinamide. It is used to treat pellagra and as a vasodilator, and it is widely used as an additive for food and feed.

2. A medicine intermediate, used in the production of isoniazid, nicotinamide, nikethamide, inositol nicotinate, etc.

3. Nicotinic acid is an important factor in delivering hydrogen and fighting pellagra in organisms; it helps maintain skin and nerve health and stimulate digestion.

4. Coenzyme and cofactor; pyridine nucleotide coenzyme; decreases the amount of low density lipoproteins in the liver and slows the fibrosis of apolipoproteins.

5. Biochemistry research, a nutritional component of tissue culture mediums.

6. Niacin feed grade is used as vitamin for poultry, swines, ruminants, fish, dogs and cats, etc.

 

Commercial Information

DeliveryWithin 15 days of order date

PaymentT/T, D/P, L/C

OriginChina

BrandVIADD

SupplierShenyang Viadd Chemical Co.,Ltd.

Price Emailsales@viaddchem.com

CertificateISO,KOSHER,HALAL,GMP, MSDS, Material Data Sheet, Non GMO,Non Allergen

Deliver PortTianjin/Qingdao

DocumentsSales Contract, Commercial Invice, Packing List, Weight List, COA, , Cetificate of Origin, Healthey Certificate, FORM A, FORM E, Policy of Indusrance, B/L, Loading container photos, packing photos, shipping advice, etc

Packing25kg net in carton with Aluminum foil bag or 1000kg woven bag

Shelf Life2 years

StorageStore in sealed containers at cool & dry place.Protect from light, moisture and pest infestation.

 

Functions of VITAMIN B3

1. Nicotinic acid is converted to niacinamide in the human body, involved in lipid metabolism, oxidation in tissue respiration and anaerobic decomposition for carbohydrate oxidation. It’s mainly used for medicine, food and feed additives field.

2. In animal feed additives, its main functions areTo prevent from skin lesions and digestive diseases; to promote animal growth, improve egg production and hatching rate, to ensure good feather growth; to treat of mucosal inflammation and ulceration; Prevent from the livestock and poultry perosis.

3. In medicine and food additives, and its main functions areto prevent of skin lesions and digestive diseases; to promote participation in the body of material and energy metabolism, to promote human growth and development; to treat a variety of mucosal inflammation and ulcers with other drugs; Strong vasodilator effect, to improve the blood supply to the body function, feature favorable effect on cerebral thrombosis, coronary heart disease, hyperlipidemia and so on; to treat nicotinic acid , nicotinamide deficiency caused by its long-term medicament of isonicotinic acid hydrazine and analogs. As a pharmaceutical intermediate, Nicotinic acid is used for production of  isoniazid, niacinamide, nikethamide and inositol nicotinate.

 

Specifications of VITAMIN B3

Product name

Vitamin B3

Appearance

White Crystalline powder

Odor

Characteristic

Taste

Characteristic

Identification

positive reaction

Specific Rotation

Should be clear and colorless

Color of solution

No more than solution Y7 or GY7

PH

2.7 - 3.3

Sulfates

300 ppm max

Nitrates

None

Absorbance of solution

0.025 max

Chromatographic purity

1% max

Residue on ignition

0.10% max

Assay

99.5-100.3%

Loss on drying

NMT5.0%

Sulphated Ash

NMT5.0%

Heavy Metals

NMT 10ppm

 

 

Total Plate Count

NMT 1000cfu/g

Yeast & Moulds

NMT 100cfu/g

E.Coli.

Negative

Salmonella

Negative

Enterobacteria

Negative

Staphylococcus aureus

Negative

 

Chemical Properties

Melting point       236-239 °C(lit.)

Boiling point        260C

density 1.473

Fp 193°C

storage temp.      0-6°C

solubility       18g/l

pka  4.85(at 25)

form      Powder

color      White to off-white

PH  2.7 (18g/l, H2O, 20)

Water Solubility   1-5 g/100 mL at 17 ºC

Merck    14,6525

BRN      109591

Stability: Stable. Incompatible with strong oxidizing agents. May be light sensitive.

InChIKey       PVNIIMVLHYAWGP-UHFFFAOYSA-N

CAS DataBase Reference  59-67-6(CAS DataBase Reference)

NIST Chemistry Reference       Niacin(59-67-6)

EPA Substance Registry System      3-Pyridinecarboxylic acid(59-67-6)

Raw Materials
Sodium hydroxide-->Nitric acid-->Potassium permanganate-->Manganese dioxide-->Cupric sulfate-->4-Chlorobenzaldehyde-->Activatedcarbon,decolor-->3-Cyanopyridine-->3-Picoline-->Ozone-->Nicotinamide-->6-Hydroxyquinoline-->Ammonium ferric citrate-->SODIUM NICOTINATE-->L-Nicotine-->Vanadium catalyst

Preparation Products
Dimethyl sulfate-->Metanilic acid-->Anthraquinone-->1-Amino anthraquinone-->5-Aminonicotinic acid-->Nicotinamide-->2-CHLOROPYRIDINE-3,4-DICARBOXYLIC ACID-->ETHYL LINOLEATE-->3-Acetylpyridine-->Fluazifop-P-butyl-->2-Aminosulfonyl-N,N-dimethylnicotinamide-->FURFURYL ALCOHOL RESIN-->6-CYANONICOTINIC ACID-->5-BROMO-3-FORMYLPYRIDINE-->2-Chloro-5-chloromethylpyridine-->3,3'-DIPICOLYLAMINE-->2-Amino-1,4-benzenedisulfonic acid-->(5-BROMO-PYRIDIN-3-YL)-METHANOL-->SODIUM NICOTINATE-->Dichlorosulfophenyl-3-methylpyrazolone-->NICOTINYL CHLORIDE HYDROCHLORIDE-->N,N-DIETHYLNICOTINAMIDE-->N-Benzylniacin

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