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ABOUT VITAMIN B3 (NIACIN, NIACINAMIDE, NICOTINIC ACID)
VIADD CHEMICAL company is one professional VITAMIN B3 (NIACIN) supplier, distibutor and exporter from China, welcome get price by email: sales@viaddchem.com
Vitamin B3 is a water-soluble vitamin, the product is white powder, odorless or nearly odorless, bitter in taste,freely soluble in water or ethanol, dissolvable in glycerin.
Vitamin B3 is easy to absorb oral, and can be widely distributed in the body, the excess metabolites or prototype quickly expel from urine. Nicotinamide is part of coenzyme I and coenzyme II, plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism, maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role.In addition, Vitamin B3 has prevention and treatment of heart block, sinus node function and anti-fast experimental arrhythmias, niacinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.
【Basic Information】
【Chemical Name】VITAMIN B3 (Niacin, Niacinamide, Nicotinic Acid)
【CAS No.】59-67-6
【EINECS No.】200-441-0
【Other Names】Nicotinic acid, Niacin; Vitamin PP; 3-Pyridinecarboxylic acid; 3-Carboxypyridine
【Specification】Food grade, Feed grade, Pharma Grade
【Molecular Formula】C6H5NO2
【Formula Weight】123.11
【Appearance】white crystals or crystalline powder
【Chemical Properties】White crystal or crystalline powder, odorless or has a slight odor, slight sour taste. Melting point is 234-237℃. Easily soluble in hot water, hot ethanol, alkaline water, propylene glycol, and chloroform. Slightly soluble in water and ethanol; 100ml room temperature water can dissolve 1.6g. Insoluble in ether and ester solutions. The PH of 1% aqueous solution is 3.0-4.0. Stable in heat, acidity and alkalinity.
【Uses】
1. This product is a type of vitamin supplement, and it is called vitamin PP along with nicotinamide. It is used to treat pellagra and as a vasodilator, and it is widely used as an additive for food and feed.
2. A medicine intermediate, used in the production of isoniazid, nicotinamide, nikethamide, inositol nicotinate, etc.
3. Nicotinic acid is an important factor in delivering hydrogen and fighting pellagra in organisms; it helps maintain skin and nerve health and stimulate digestion.
4. Coenzyme and cofactor; pyridine nucleotide coenzyme; decreases the amount of low density lipoproteins in the liver and slows the fibrosis of apolipoproteins.
5. Biochemistry research, a nutritional component of tissue culture mediums.
6. Niacin feed grade is used as vitamin for poultry, swines, ruminants, fish, dogs and cats, etc.
【Commercial Information】
【Delivery】Within 15 days of order date
【Payment】T/T, D/P, L/C
【Origin】China
【Brand】VIADD
【Supplier】Shenyang Viadd Chemical Co.,Ltd.
【Price Email】sales@viaddchem.com
【Certificate】ISO,KOSHER,HALAL,GMP, MSDS, Material Data Sheet, Non GMO,Non Allergen
【Deliver Port】Tianjin/Qingdao
【Documents】Sales Contract, Commercial Invice, Packing List, Weight List, COA, , Cetificate of Origin, Healthey Certificate, FORM A, FORM E, Policy of Indusrance, B/L, Loading container photos, packing photos, shipping advice, etc
【Packing】25kg net in carton with Aluminum foil bag or 1000kg woven bag
【Shelf Life】2 years
【Storage】Store in sealed containers at cool & dry place.Protect from light, moisture and pest infestation.
【Functions of VITAMIN B3】
1. Nicotinic acid is converted to niacinamide in the human body, involved in lipid metabolism, oxidation in tissue respiration and anaerobic decomposition for carbohydrate oxidation. It’s mainly used for medicine, food and feed additives field.
2. In animal feed additives, its main functions are:To prevent from skin lesions and digestive diseases; to promote animal growth, improve egg production and hatching rate, to ensure good feather growth; to treat of mucosal inflammation and ulceration; Prevent from the livestock and poultry perosis.
3. In medicine and food additives, and its main functions are:to prevent of skin lesions and digestive diseases; to promote participation in the body of material and energy metabolism, to promote human growth and development; to treat a variety of mucosal inflammation and ulcers with other drugs; Strong vasodilator effect, to improve the blood supply to the body function, feature favorable effect on cerebral thrombosis, coronary heart disease, hyperlipidemia and so on; to treat nicotinic acid , nicotinamide deficiency caused by its long-term medicament of isonicotinic acid hydrazine and analogs. As a pharmaceutical intermediate, Nicotinic acid is used for production of isoniazid, niacinamide, nikethamide and inositol nicotinate.
【Specifications of VITAMIN B3】
Product name |
Vitamin B3 |
Appearance |
White Crystalline powder |
Odor |
Characteristic |
Taste |
Characteristic |
Identification |
positive reaction |
Specific Rotation |
Should be clear and colorless |
Color of solution |
No more than solution Y7 or GY7 |
PH |
2.7 - 3.3 |
Sulfates |
300 ppm max |
Nitrates |
None |
Absorbance of solution |
0.025 max |
Chromatographic purity |
1% max |
Residue on ignition |
0.10% max |
Assay |
99.5-100.3% |
Loss on drying |
NMT5.0% |
Sulphated Ash |
NMT5.0% |
Heavy Metals |
NMT 10ppm |
|
|
Total Plate Count |
NMT 1000cfu/g |
Yeast & Moulds |
NMT 100cfu/g |
E.Coli. |
Negative |
Salmonella |
Negative |
Enterobacteria |
Negative |
Staphylococcus aureus |
Negative |
【Chemical Properties】
Melting point 236-239 °C(lit.)
Boiling point 260C
density 1.473
Fp 193°C
storage temp. 0-6°C
solubility 18g/l
pka 4.85(at 25℃)
form Powder
color White to off-white
PH 2.7 (18g/l, H2O, 20℃)
Water Solubility 1-5 g/100 mL at 17 ºC
Merck 14,6525
BRN 109591
Stability: Stable. Incompatible with strong oxidizing agents. May be light sensitive.
InChIKey PVNIIMVLHYAWGP-UHFFFAOYSA-N
CAS DataBase Reference 59-67-6(CAS DataBase Reference)
NIST Chemistry Reference Niacin(59-67-6)
EPA Substance Registry System 3-Pyridinecarboxylic acid(59-67-6)
【Raw Materials】
Sodium hydroxide-->Nitric acid-->Potassium permanganate-->Manganese dioxide-->Cupric sulfate-->4-Chlorobenzaldehyde-->Activatedcarbon,decolor-->3-Cyanopyridine-->3-Picoline-->Ozone-->Nicotinamide-->6-Hydroxyquinoline-->Ammonium ferric citrate-->SODIUM NICOTINATE-->L-Nicotine-->Vanadium catalyst
【Preparation Products】
Dimethyl sulfate-->Metanilic acid-->Anthraquinone-->1-Amino anthraquinone-->5-Aminonicotinic acid-->Nicotinamide-->2-CHLOROPYRIDINE-3,4-DICARBOXYLIC ACID-->ETHYL LINOLEATE-->3-Acetylpyridine-->Fluazifop-P-butyl-->2-Aminosulfonyl-N,N-dimethylnicotinamide-->FURFURYL ALCOHOL RESIN-->6-CYANONICOTINIC ACID-->5-BROMO-3-FORMYLPYRIDINE-->2-Chloro-5-chloromethylpyridine-->3,3'-DIPICOLYLAMINE-->2-Amino-1,4-benzenedisulfonic acid-->(5-BROMO-PYRIDIN-3-YL)-METHANOL-->SODIUM NICOTINATE-->Dichlorosulfophenyl-3-methylpyrazolone-->NICOTINYL CHLORIDE HYDROCHLORIDE-->N,N-DIETHYLNICOTINAMIDE-->N-Benzylniacin
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